谱析（上海）生物科技有限公司提供——Antiepileptics in Serum 质谱诊断方案
 
一、说明
Antiepileptic drugs (AED) are the mainstay of epilepsy treatment. The medication enables the patient to live free of epileptic seizures. Depending on the type of epilepsy, several AEDs with diverse activity mechanisms may be used for the management of the disease. For the monitoring of the drug level, this ClinRep@ Complete Kit allows the simultaneous determination of 13* AEDs and metabolites. 
 
* Carbamazepine, carbamazepine-epoxide, N-desmethylmethsuximide, eslicarbazepine, ethosuximide,10-hydroxycarbamazepine, lamotrigine, oxcarbazepine, phenylethylmalonamide (PEMA), phenobarbital, phenytoin, primidone, sulthiame
 
二、产品优势
（1）Simultaneous analysis of 13 antiepileptic drugs
（2）Efficient sample clean-up
（3）Robust and fast chromatography (injection interval: 15 min)
 
三、测试数据
Linearity:                  Lamotrig., Sulthiame:
                            0.5- 50 μg/ml
                            Other Antiepileptics:
                            0.3- 300 ug/ml
Recovery:                   95 - 105 %
LOD:                        Lamotrig., Sulthiame:        
                            0.2 μg/ml
                            Other Antiepileptics:
                            0.1 μg/ml
LLOQ:                       Lamotrig., Sulthiame:
                            0.5 μg/ml
                            Other Antiepileptics:
                            0.3 μg/ml
Intraassay precision:      2.3 %
Interassay precision:       2.8 %
 
 
 
四、高效液相色谱参数
Pump:                       isocratic pump, flow rate: 1.0 ml/min
Injection volume:           10 μI
Injection interval:         15 min
UV/VIS-Detector:            
Lamotrig., Sulthiame:      265 nm
Other Antiepileptics:      205 nm 
HPLC-Thermostat:            55°C
 
五、样品制备
 
 
 
六、订购信息
 

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